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Pantoprazole inhibits human gastric adenocarcinoma SGC-7901 cells by downregulating the expression of pyruvate kinase M2

The Warburg effect is important in tumor growth. The human M2 isoform of pyruvate kinase (PKM2) is a key enzyme that regulates aerobic glycolysis in tumor cells. Recent studies have demonstrated that PKM2 is a potential target for cancer therapy. The present study investigated the effects of pantopr...

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Detalles Bibliográficos
Publicado en:Oncol Lett
Main Authors: SHEN, YONGHUA, CHEN, MIN, HUANG, SHULING, ZOU, XIAOPING
Formato: Artigo
Idioma:Inglês
Publicado: D.A. Spandidos 2016
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC4727057/
https://ncbi.nlm.nih.gov/pubmed/26870273
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3892/ol.2015.3912
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