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Engineering Infectious cDNAs of Coronavirus as Bacterial Artificial Chromosomes

The large size of the coronavirus (CoV) genome (around 30 kb) and the instability in bacteria of plasmids carrying CoV replicase sequences represent serious restrictions for the development of CoV infectious clones using reverse genetic systems similar to those used for smaller positive sense RNA vi...

Täydet tiedot

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Bibliografiset tiedot
Julkaisussa:Coronaviruses
Päätekijät: Almazán, Fernando, Márquez-Jurado, Silvia, Nogales, Aitor, Enjuanes, Luis
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: 2014
Aiheet:
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC4726977/
https://ncbi.nlm.nih.gov/pubmed/25720478
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/978-1-4939-2438-7_13
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