Type I and Type II Interferon Coordinately Regulate Suppressive Dendritic Cell Fate and Function during Viral Persistence

Persistent viral infections are simultaneously associated with chronic inflammation and highly potent immunosuppressive programs mediated by IL-10 and PDL1 that attenuate antiviral T cell responses. Inhibiting these suppressive signals enhances T cell function to control persistent infection; yet, t...

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Detaylı Bibliyografya
Yayımlandı:PLoS Pathog
Asıl Yazarlar: Cunningham, Cameron R., Champhekar, Ameya, Tullius, Michael V., Dillon, Barbara Jane, Zhen, Anjie, de la Fuente, Justin Rafael, Herskovitz, Jonathan, Elsaesser, Heidi, Snell, Laura M., Wilson, Elizabeth B., de la Torre, Juan Carlos, Kitchen, Scott G., Horwitz, Marcus A., Bensinger, Steven J., Smale, Stephen T., Brooks, David G.
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: Public Library of Science 2016
Konular:
Research Article
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC4726812/
https://ncbi.nlm.nih.gov/pubmed/26808628
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.ppat.1005356
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