Characterization of Heterogeneous Prostate Tumors in Targeted Pten Knockout Mice

Previously, we generated a preclinical mouse prostate tumor model based on PSA-Cre driven inactivation of Pten. In this model homogeneous hyperplastic prostates (4-5m) developed at older age (>10m) into tumors. Here, we describe the molecular and histological characterization of the tumors in ord...

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Dettagli Bibliografici
Pubblicato in:PLoS One
Autori principali: Korsten, Hanneke, Ziel-van der Made, Angelique C. J., van Weerden, Wytske M., van der Kwast, Theo, Trapman, Jan, Van Duijn, Petra W.
Natura: Artigo
Lingua:Inglês
Pubblicazione: Public Library of Science 2016
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Research Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4726760/
https://ncbi.nlm.nih.gov/pubmed/26807730
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0147500
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