Coenzyme Q Biosynthesis: Evidence for a Substrate Access Channel in the FAD-Dependent Monooxygenase Coq6

Coq6 is an enzyme involved in the biosynthesis of coenzyme Q, a polyisoprenylated benzoquinone lipid essential to the function of the mitochondrial respiratory chain. In the yeast Saccharomyces cerevisiae, this putative flavin-dependent monooxygenase is proposed to hydroxylate the benzene ring of co...

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Detalhes bibliográficos
Publicado no:PLoS Comput Biol
Main Authors: Ismail, Alexandre, Leroux, Vincent, Smadja, Myriam, Gonzalez, Lucie, Lombard, Murielle, Pierrel, Fabien, Mellot-Draznieks, Caroline, Fontecave, Marc
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2016
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4726752/
https://ncbi.nlm.nih.gov/pubmed/26808124
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pcbi.1004690
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