Short-term assessment of BCR repertoires of SLE patients after high dose glucocorticoid therapy with high-throughput sequencing

We analyze and assess BCR repertoires of SLE patients before and after high dose glucocorticoid therapy to address two fundamental questions: (1) After the treatment, how the BCR repertoire of SLE patient change on the clone level? (2) How to screen putative autoantibody clone set from BCR repertoir...

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Veröffentlicht in:Springerplus
Hauptverfasser: Shi, Bin, Yu, Jiang, Ma, Long, Ma, Qingqing, Liu, Chunmei, Sun, Suhong, Ma, Rui, Yao, Xinsheng
Format: Artigo
Sprache:Inglês
Veröffentlicht: Springer International Publishing 2016
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Research
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4726643/
https://ncbi.nlm.nih.gov/pubmed/26844022
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s40064-016-1709-4
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