Deletion of ASK1 Protects against Hyperoxia-Induced Acute Lung Injury

Apoptosis signal-regulating kinase 1 (ASK1), a member of the MAPK kinase kinase kinase (MAP3K) family, is activated by various stimuli, which include oxidative stress, endoplasmic reticulum (ER) stress, calcium influx, DNA damage-inducing agents and receptor-mediated signaling through tumor necrosis...

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Bibliographic Details
Published in:PLoS One
Main Authors: Fukumoto, Jutaro, Cox, Ruan, Fukumoto, Itsuko, Cho, Young, Parthasarathy, Prasanna Tamarapu, Galam, Lakshmi, Lockey, Richard F., Kolliputi, Narasaiah
Format: Artigo
Language:Inglês
Published: Public Library of Science 2016
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Research Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4726536/
https://ncbi.nlm.nih.gov/pubmed/26807721
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0147652
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