NLRP3 deletion protects from hyperoxia-induced acute lung injury

Inspiration of a high concentration of oxygen, a therapy for acute lung injury (ALI), could unexpectedly lead to reactive oxygen species (ROS) production and hyperoxia-induced acute lung injury (HALI). Nucleotide-binding domain and leucine-rich repeat PYD-containing protein 3 (NLRP3) senses the ROS,...

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Main Authors: Fukumoto, Jutaro, Fukumoto, Itsuko, Parthasarathy, Prasanna Tamarapu, Cox, Ruan, Huynh, Bao, Ramanathan, Gurukumar Kollongod, Venugopal, Rajan Babu, Allen-Gipson, Diane S., Lockey, Richard F., Kolliputi, Narasaiah
Formato: Artigo
Idioma:Inglês
Publicado em: American Physiological Society 2013
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Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3725631/
https://ncbi.nlm.nih.gov/pubmed/23636457
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajpcell.00086.2013
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