Post-transcriptional Control of Tumor Cell Autonomous Metastatic Potential by CCR4-NOT Deadenylase CNOT7

Accumulating evidence supports the role of an aberrant transcriptome as a driver of metastatic potential. Deadenylation is a general regulatory node for post-transcriptional control by microRNAs and other determinants of RNA stability. Previously, we demonstrated that the CCR4-NOT scaffold component...

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Udgivet i:PLoS Genet
Main Authors: Faraji, Farhoud, Hu, Ying, Yang, Howard H., Lee, Maxwell P., Winkler, G. Sebastian, Hafner, Markus, Hunter, Kent W.
Format: Artigo
Sprog:Inglês
Udgivet: Public Library of Science 2016
Fag:
Research Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4726497/
https://ncbi.nlm.nih.gov/pubmed/26807845
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pgen.1005820
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