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Photoactivated adenylyl cyclase (PAC) reveals novel mechanisms underlying cAMP-dependent axonal morphogenesis

Spatiotemporal regulation of axonal branching and elongation is essential in the development of refined neural circuits. cAMP is a key regulator of axonal growth; however, whether and how intracellular cAMP regulates axonal branching and elongation remain unclear, mainly because tools to spatiotempo...

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Salvato in:
Dettagli Bibliografici
Pubblicato in:Sci Rep
Autori principali: Zhou, Zhiwen, Tanaka, Kenji F., Matsunaga, Shigeru, Iseki, Mineo, Watanabe, Masakatsu, Matsuki, Norio, Ikegaya, Yuji, Koyama, Ryuta
Natura: Artigo
Lingua:Inglês
Pubblicazione: Nature Publishing Group 2016
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4726437/
https://ncbi.nlm.nih.gov/pubmed/26795422
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep19679
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