Virus-specific antibodies allow viral replication in the marginal zone, thereby promoting CD8(+) T-cell priming and viral control

Clinically used human vaccination aims to induce specific antibodies that can guarantee long-term protection against a pathogen. The reasons that other immune components often fail to induce protective immunity are still debated. Recently we found that enforced viral replication in secondary lymphoi...

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Publicado en:Sci Rep
Main Authors: Duhan, Vikas, Khairnar, Vishal, Friedrich, Sarah-Kim, Zhou, Fan, Gassa, Asmae, Honke, Nadine, Shaabani, Namir, Gailus, Nicole, Botezatu, Lacramioara, Khandanpour, Cyrus, Dittmer, Ulf, Häussinger, Dieter, Recher, Mike, Hardt, Cornelia, Lang, Philipp A., Lang, Karl S.
Formato: Artigo
Idioma:Inglês
Publicado: Nature Publishing Group 2016
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Article
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC4726415/
https://ncbi.nlm.nih.gov/pubmed/26805453
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep19191
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