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Induction of cell death by the novel proteasome inhibitor marizomib in glioblastoma in vitro and in vivo
New therapies for glioblastoma (GBM) are needed, as five-year survival is <10%. The proteasome inhibitor marizomib (MRZ) has inhibitory and death-inducing properties unique from previous inhibitors such as bortezomib (BTZ), and has not been well examined in GBM. We evaluated the mechanism of deat...
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| Publicado no: | Sci Rep |
|---|---|
| Main Authors: | , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Nature Publishing Group
2016
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4726202/ https://ncbi.nlm.nih.gov/pubmed/26804704 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep18953 |
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