Different human vaccine adjuvants promote distinct antigen-independent immunological signatures tailored to different pathogens

The majority of vaccine candidates in clinical development are highly purified proteins and peptides relying on adjuvants to enhance and/or direct immune responses. Despite the acknowledged need for novel adjuvants, there are still very few adjuvants in licensed human vaccines. A vast number of adju...

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Publicado no:Sci Rep
Main Authors: Knudsen, Niels Peter H., Olsen, Anja, Buonsanti, Cecilia, Follmann, Frank, Zhang, Yuan, Coler, Rhea N., Fox, Christopher B., Meinke, Andreas, D´Oro, Ugo, Casini, Daniele, Bonci, Alessandra, Billeskov, Rolf, De Gregorio, Ennio, Rappuoli, Rino, Harandi, Ali M., Andersen, Peter, Agger, Else Marie
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2016
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4726129/
https://ncbi.nlm.nih.gov/pubmed/26791076
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep19570
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