Meta-analysis of lipid-traits in Hispanics identifies novel loci, population-specific effects, and tissue-specific enrichment of eQTLs

We performed genome-wide meta-analysis of lipid traits on three samples of Mexican and Mexican American ancestry comprising 4,383 individuals, and followed up significant and highly suggestive associations in three additional Hispanic samples comprising 7,876 individuals. Genome-wide significant sig...

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Publicat a:Sci Rep
Autors principals: Below, Jennifer E., Parra, Esteban J., Gamazon, Eric R., Torres, Jason, Krithika, S., Candille, Sophie, Lu, Yingchang, Manichakul, Ani, Peralta-Romero, Jesus, Duan, Qing, Li, Yun, Morris, Andrew P., Gottesman, Omri, Bottinger, Erwin, Wang, Xin-Qun, Taylor, Kent D., Ida Chen, Y.-D., Rotter, Jerome I., Rich, Stephen S., Loos, Ruth J. F., Tang, Hua, Cox, Nancy J., Cruz, Miguel, Hanis, Craig L., Valladares-Salgado, Adan
Format: Artigo
Idioma:Inglês
Publicat: Nature Publishing Group 2016
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Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4726092/
https://ncbi.nlm.nih.gov/pubmed/26780889
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep19429
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