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Cytotoxic polyfunctionality maturation of cytomegalovirus-pp65-specific CD4 + and CD8 + T-cell responses in older adults positively correlates with response size

Cytomegalovirus (CMV) infection is one of the most common persistent viral infections in humans worldwide and is epidemiologically associated with many adverse health consequences during aging. Previous studies yielded conflicting results regarding whether large, CMV-specific T-cell expansions maint...

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Bibliografske podrobnosti
izdano v:Sci Rep
Main Authors: Chiu, Yen-Ling, Lin, Chung-Hao, Sung, Bo-Yi, Chuang, Yi-Fang, Schneck, Jonathan P., Kern, Florian, Pawelec, Graham, Wang, George C.
Format: Artigo
Jezik:Inglês
Izdano: Nature Publishing Group 2016
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC4726016/
https://ncbi.nlm.nih.gov/pubmed/26778409
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep19227
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