Cyclosporin A and tacrolimus reduce T-cell polyfunctionality but not interferon-γ responses directed at cytomegalovirus

Cytomegalovirus (CMV) -specific immunity is often estimated by the number of in vitro CMV antigen-inducible interferon-γ-positive (IFN-γ(+)) T cells. However, recent work indicates that simultaneous production of IFN-γ, tumour necrosis factor-α (TNF-α) and interleukin-2 (IL-2) (referred to as ‘polyf...

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Detalhes bibliográficos
Main Authors: Fuhrmann, Stephan, Lachmann, Raskit, Streitz, Mathias, Hetzer, Roland, Volk, Hans-Dieter, Lehmkuhl, Hans, Kern, Florian
Formato: Artigo
Idioma:Inglês
Publicado em: Blackwell Science Inc 2012
Assuntos:
Original Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3401979/
https://ncbi.nlm.nih.gov/pubmed/22533718
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1365-2567.2012.03594.x
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