Polyfunctional T Cells Accumulate in Large Human Cytomegalovirus-Specific T Cell Responses

Large cytomegalovirus (CMV)-specific CD8 T-cell responses are observed in both young and, somewhat more often, old people. Frequent CMV reactivation is thought to exhaust these cells and render them dysfunctional so that larger numbers of them are needed to control CMV. Expansions of CMV-specific CD...

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Detalhes bibliográficos
Main Authors: Lachmann, Raskit, Bajwa, Martha, Vita, Serena, Smith, Helen, Cheek, Elizabeth, Akbar, Arne, Kern, Florian
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2012
Assuntos:
Pathogenesis and Immunity
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3255847/
https://ncbi.nlm.nih.gov/pubmed/22072753
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.00873-11
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