Polyfunctional T Cells Accumulate in Large Human Cytomegalovirus-Specific T Cell Responses

Large cytomegalovirus (CMV)-specific CD8 T-cell responses are observed in both young and, somewhat more often, old people. Frequent CMV reactivation is thought to exhaust these cells and render them dysfunctional so that larger numbers of them are needed to control CMV. Expansions of CMV-specific CD...

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Hlavní autoři: Lachmann, Raskit, Bajwa, Martha, Vita, Serena, Smith, Helen, Cheek, Elizabeth, Akbar, Arne, Kern, Florian
Médium: Artigo
Jazyk:Inglês
Vydáno: American Society for Microbiology 2012
Témata:
Pathogenesis and Immunity
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3255847/
https://ncbi.nlm.nih.gov/pubmed/22072753
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.00873-11
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