Polyfunctional T Cells Accumulate in Large Human Cytomegalovirus-Specific T Cell Responses

Large cytomegalovirus (CMV)-specific CD8 T-cell responses are observed in both young and, somewhat more often, old people. Frequent CMV reactivation is thought to exhaust these cells and render them dysfunctional so that larger numbers of them are needed to control CMV. Expansions of CMV-specific CD...

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Главные авторы: Lachmann, Raskit, Bajwa, Martha, Vita, Serena, Smith, Helen, Cheek, Elizabeth, Akbar, Arne, Kern, Florian
Формат: Artigo
Язык:Inglês
Опубликовано: American Society for Microbiology 2012
Предметы:
Pathogenesis and Immunity
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC3255847/
https://ncbi.nlm.nih.gov/pubmed/22072753
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.00873-11
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