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Cytotoxic polyfunctionality maturation of cytomegalovirus-pp65-specific CD4 + and CD8 + T-cell responses in older adults positively correlates with response size

Cytomegalovirus (CMV) infection is one of the most common persistent viral infections in humans worldwide and is epidemiologically associated with many adverse health consequences during aging. Previous studies yielded conflicting results regarding whether large, CMV-specific T-cell expansions maint...

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Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:Sci Rep
Prif Awduron: Chiu, Yen-Ling, Lin, Chung-Hao, Sung, Bo-Yi, Chuang, Yi-Fang, Schneck, Jonathan P., Kern, Florian, Pawelec, Graham, Wang, George C.
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: Nature Publishing Group 2016
Pynciau:
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC4726016/
https://ncbi.nlm.nih.gov/pubmed/26778409
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep19227
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