miRNA-378 reverses chemoresistance to cisplatin in lung adenocarcinoma cells by targeting secreted clusterin

Cisplatin resistance is a major obstacle in the treatment of NSCLC, and its mechanism has not been fully elucidated. The objectives of the study were to determine the role of miR-378 in the sensitivity of lung adenocarcinoma cells to cisplatin (cDDP) and its working mechanism. With TargetScan and lu...

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Publicat a:Sci Rep
Autors principals: Chen, Xuesong, Jiang, Ying, Huang, Zheping, Li, Dandan, Chen, Xiaodi, Cao, Mengru, Meng, Qingwei, Pang, Hui, Sun, Lichun, Zhao, Yanbin, Cai, Li
Format: Artigo
Idioma:Inglês
Publicat: Nature Publishing Group 2016
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Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4725983/
https://ncbi.nlm.nih.gov/pubmed/26781643
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep19455
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