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EHD1 confers resistance to cisplatin in non-small cell lung cancer by regulating intracellular cisplatin concentrations

BACKGROUND: Non-small cell lung cancer (NSCLC) is one of the most aggressive types of cancer. However, resistance to cisplatin (CDDP) remains a major challenge in NSCLC treatment. The purpose of this study was to investigate the ability of EHD1 [Eps15 homology (EH) domain - containing protein 1] to...

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Publicat a:BMC Cancer
Autors principals: Gao, Jing, Meng, Qingwei, Zhao, Yanbin, Chen, Xuesong, Cai, Li
Format: Artigo
Idioma:Inglês
Publicat: BioMed Central 2016
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4944258/
https://ncbi.nlm.nih.gov/pubmed/27411790
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12885-016-2527-3
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