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Effects of K-115 (Ripasudil), a novel ROCK inhibitor, on trabecular meshwork and Schlemm’s canal endothelial cells

Ripasudil hydrochloride hydrate (K-115), a specific Rho-associated coiled-coil containing protein kinase (ROCK) inhibitor, was the first ophthalmic solution developed for the treatment of glaucoma and ocular hypertension in Japan. Topical administration of K-115 decreased intraocular pressure (IOP)...

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Podrobná bibliografie
Vydáno v:Sci Rep
Hlavní autoři: Kaneko, Yoshio, Ohta, Masayuki, Inoue, Toshihiro, Mizuno, Ken, Isobe, Tomoyuki, Tanabe, Sohei, Tanihara, Hidenobu
Médium: Artigo
Jazyk:Inglês
Vydáno: Nature Publishing Group 2016
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4725980/
https://ncbi.nlm.nih.gov/pubmed/26782355
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep19640
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