Additive Intraocular Pressure-Lowering Effects of Ripasudil with Glaucoma Therapeutic Agents in Rabbits and Monkeys

Ripasudil hydrochloride hydrate (K-115), a specific Rho-associated coiled-coil containing protein kinase (ROCK) inhibitor, is developed for the treatment of glaucoma and ocular hypertension. Topical administration of ripasudil decreases intraocular pressure (IOP) by increasing conventional outflow t...

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Detalhes bibliográficos
Publicado no:J Ophthalmol
Main Authors: Kaneko, Yoshio, Ohta, Masayuki, Isobe, Tomoyuki, Nakamura, Yuto, Mizuno, Ken
Formato: Artigo
Idioma:Inglês
Publicado em: Hindawi 2017
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5429944/
https://ncbi.nlm.nih.gov/pubmed/28540083
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/2017/7079645
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