Teratocarcinomas Arising from Allogeneic Induced Pluripotent Stem Cell-Derived Cardiac Tissue Constructs Provoked Host Immune Rejection in Mice

Transplantation of induced pluripotent stem cell-derived cardiac tissue constructs is a promising regenerative treatment for cardiac failure: however, its tumourigenic potential is concerning. We hypothesised that the tumourigenic potential may be eliminated by the host immune response after allogen...

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Udgivet i:Sci Rep
Main Authors: Kawamura, Ai, Miyagawa, Shigeru, Fukushima, Satsuki, Kawamura, Takuji, Kashiyama, Noriyuki, Ito, Emiko, Watabe, Tadashi, Masuda, Shigeo, Toda, Koichi, Hatazawa, Jun, Morii, Eiichi, Sawa, Yoshiki
Format: Artigo
Sprog:Inglês
Udgivet: Nature Publishing Group 2016
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4725880/
https://ncbi.nlm.nih.gov/pubmed/26763872
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep19464
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