Development of PET Imaging to Visualize Activated Macrophages Accumulated in the Transplanted iPSc-Derived Cardiac Myocytes of Allogeneic Origin for Detecting the Immune Rejection of Allogeneic Cell Transplants in Mice

Allogeneic transplantation (Tx) of induced pluripotent stem cells (iPSCs) is a promising tissue regeneration therapy. However, this inevitably induces macrophage-mediated immune response against the graft, limiting its therapeutic efficacy. Monitoring the magnitude of the immune response using imagi...

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Dettagli Bibliografici
Pubblicato in:PLoS One
Autori principali: Kashiyama, Noriyuki, Miyagawa, Shigeru, Fukushima, Satsuki, Kawamura, Takuji, Kawamura, Ai, Yoshida, Shohei, Harada, Akima, Watabe, Tadashi, Kanai, Yasukazu, Toda, Koichi, Hatazawa, Jun, Sawa, Yoshiki
Natura: Artigo
Lingua:Inglês
Pubblicazione: Public Library of Science 2016
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Research Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC5145152/
https://ncbi.nlm.nih.gov/pubmed/27930666
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0165748
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