Identification of Immunogenic Cytotoxic T Lymphocyte Epitopes Containing Drug Resistance Mutations in Antiretroviral Treatment-Naïve HIV-Infected Individuals

BACKGROUND: Therapeutic HIV vaccines may prove helpful to intensify antiretroviral treatment (ART) efficacy and may be an integral part of future cure strategies. METHODS: We examined IFN-gamma ELISpot responses to a panel of 218 HIV clade B consensus-based HIV protease-reverse transcriptase peptide...

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Опубликовано в: :PLoS One
Главные авторы: Blanco-Heredia, Juan, Lecanda, Aarón, Valenzuela-Ponce, Humberto, Brander, Christian, Ávila-Ríos, Santiago, Reyes-Terán, Gustavo
Формат: Artigo
Язык:Inglês
Опубликовано: Public Library of Science 2016
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Research Article
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC4725752/
https://ncbi.nlm.nih.gov/pubmed/26808823
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0147571
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