Identification of Immunogenic Cytotoxic T Lymphocyte Epitopes Containing Drug Resistance Mutations in Antiretroviral Treatment-Naïve HIV-Infected Individuals

BACKGROUND: Therapeutic HIV vaccines may prove helpful to intensify antiretroviral treatment (ART) efficacy and may be an integral part of future cure strategies. METHODS: We examined IFN-gamma ELISpot responses to a panel of 218 HIV clade B consensus-based HIV protease-reverse transcriptase peptide...

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Detalhes bibliográficos
Publicado no:PLoS One
Main Authors: Blanco-Heredia, Juan, Lecanda, Aarón, Valenzuela-Ponce, Humberto, Brander, Christian, Ávila-Ríos, Santiago, Reyes-Terán, Gustavo
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2016
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4725752/
https://ncbi.nlm.nih.gov/pubmed/26808823
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0147571
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