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ChREBP Regulates Itself and Metabolic Genes Implicated in Lipid Accumulation in β–Cell Line

Carbohydrate response element binding protein (ChREBP) is an important transcription factor that regulates a variety of glucose-responsive genes in hepatocytes. To date, only two natural isoforms, Chrebpα and Chrebpβ, have been identified. Although ChREBP is known to be expressed in pancreatic β cel...

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Détails bibliographiques
Publié dans:PLoS One
Auteurs principaux: Sae-Lee, Chanachai, Moolsuwan, Kanya, Chan, Lawrence, Poungvarin, Naravat
Format: Artigo
Langue:Inglês
Publié: Public Library of Science 2016
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Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC4725739/
https://ncbi.nlm.nih.gov/pubmed/26808438
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0147411
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