Loss of the BBSome perturbs endocytic trafficking and disrupts virulence of Trypanosoma brucei

Cilia (eukaryotic flagella) are present in diverse eukaryotic lineages and have essential motility and sensory functions. The cilium’s capacity to sense and transduce extracellular signals depends on dynamic trafficking of ciliary membrane proteins. This trafficking is often mediated by the Bardet–B...

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Dades bibliogràfiques
Publicat a:Proc Natl Acad Sci U S A
Autors principals: Langousis, Gerasimos, Shimogawa, Michelle M., Saada, Edwin A., Vashisht, Ajay A., Spreafico, Roberto, Nager, Andrew R., Barshop, William D., Nachury, Maxence V., Wohlschlegel, James A., Hill, Kent L.
Format: Artigo
Idioma:Inglês
Publicat: National Academy of Sciences 2016
Matèries:
Biological Sciences
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4725476/
https://ncbi.nlm.nih.gov/pubmed/26721397
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1518079113
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