Loss of the BBSome perturbs endocytic trafficking and disrupts virulence of Trypanosoma brucei

Cilia (eukaryotic flagella) are present in diverse eukaryotic lineages and have essential motility and sensory functions. The cilium’s capacity to sense and transduce extracellular signals depends on dynamic trafficking of ciliary membrane proteins. This trafficking is often mediated by the Bardet–B...

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Detalhes bibliográficos
Publicado no:Proc Natl Acad Sci U S A
Main Authors: Langousis, Gerasimos, Shimogawa, Michelle M., Saada, Edwin A., Vashisht, Ajay A., Spreafico, Roberto, Nager, Andrew R., Barshop, William D., Nachury, Maxence V., Wohlschlegel, James A., Hill, Kent L.
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2016
Assuntos:
Biological Sciences
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4725476/
https://ncbi.nlm.nih.gov/pubmed/26721397
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1518079113
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