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PCNA appears in two populations of slow and fast diffusion with a constant ratio throughout S-phase in replicating mammalian cells

DNA replication is a fundamental cellular process that precedes cell division. Proliferating cell nuclear antigen (PCNA) is a central scaffold protein that orchestrates DNA replication by recruiting many factors essential for the replication machinery. We studied the mobility of PCNA in live mammali...

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Detalhes bibliográficos
Publicado no:Sci Rep
Main Authors: Zessin, Patrick J. M., Sporbert, Anje, Heilemann, Mike
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4725372/
https://ncbi.nlm.nih.gov/pubmed/26758689
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep18779
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