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Amantelides A and B, Polyhydroxylated Macrolides with Differential Broad Spectrum Cytotoxicity from a Guamanian Marine Cyanobacterium

Cytotoxicity-guided fractionation of a Guamanian cyanobacterial collection yielded the new compounds amantelides A (1) and B (2). These polyketides are characterized by a 40-membered macrolactone ring consisting of a 1,3-diol and contiguous 1,5-diol units and a tert-butyl substituent. Amantelide A (...

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Detalhes bibliográficos
Publicado no:J Nat Prod
Main Authors: Salvador-Reyes, Lilibeth A., Sneed, Jennifer, Paul, Valerie J., Luesch, Hendrik
Formato: Artigo
Idioma:Inglês
Publicado em: 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4725301/
https://ncbi.nlm.nih.gov/pubmed/26204500
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acs.jnatprod.5b00293
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