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Targeted Natural Products Discovery from Marine Cyanobacteria Using Combined Phylogenetic and Mass Spectrometric Evaluation
Combined phylogenetic and HPLC-MS-based natural products dereplication methods aimed at identifying cyanobacterial collections containing the potent cytotoxins largazole, dolastatin 10 and symplostatin 1 were developed. The profiling of the phylogeny, chemical space, and antiproliferative activity o...
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| Publicado no: | J Nat Prod |
|---|---|
| Main Authors: | , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2015
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4724867/ https://ncbi.nlm.nih.gov/pubmed/25635943 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/np500931q |
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