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Targeted Natural Products Discovery from Marine Cyanobacteria Using Combined Phylogenetic and Mass Spectrometric Evaluation

Combined phylogenetic and HPLC-MS-based natural products dereplication methods aimed at identifying cyanobacterial collections containing the potent cytotoxins largazole, dolastatin 10 and symplostatin 1 were developed. The profiling of the phylogeny, chemical space, and antiproliferative activity o...

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Bibliografiska uppgifter
I publikationen:J Nat Prod
Huvudupphovsmän: Salvador-Reyes, Lilibeth A., Engene, Niclas, Paul, Valerie J., Luesch, Hendrik
Materialtyp: Artigo
Språk:Inglês
Publicerad: 2015
Ämnen:
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC4724867/
https://ncbi.nlm.nih.gov/pubmed/25635943
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/np500931q
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