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When stem cells grow old: phenotypes and mechanisms of stem cell aging

All multicellular organisms undergo a decline in tissue and organ function as they age. An attractive theory is that a loss in stem cell number and/or activity over time causes this decline. In accordance with this theory, aging phenotypes have been described for stem cells of multiple tissues, incl...

Ausführliche Beschreibung

Gespeichert in:
Bibliographische Detailangaben
Veröffentlicht in:Development
Hauptverfasser: Schultz, Michael B., Sinclair, David A.
Format: Artigo
Sprache:Inglês
Veröffentlicht: The Company of Biologists Ltd 2016
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4725211/
https://ncbi.nlm.nih.gov/pubmed/26732838
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1242/dev.130633
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