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Herpesviral ICP0 Protein Promotes Two Waves of Heterochromatin Removal on an Early Viral Promoter during Lytic Infection

Herpesviruses must contend with host cell epigenetic silencing responses acting on their genomes upon entry into the host cell nucleus. In this study, we confirmed that unchromatinized herpes simplex virus 1 (HSV-1) genomes enter primary human foreskin fibroblasts and are rapidly subjected to assemb...

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Bibliografiske detaljer
Udgivet i:mBio
Main Authors: Lee, Jennifer S., Raja, Priya, Knipe, David M.
Format: Artigo
Sprog:Inglês
Udgivet: American Society of Microbiology 2016
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4725016/
https://ncbi.nlm.nih.gov/pubmed/26758183
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/mBio.02007-15
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