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Herpesviral latency-associated transcript gene promotes assembly of heterochromatin on viral lytic-gene promoters in latent infection

Herpes simplex virus (HSV) persists in its human host and evades the immune response by undergoing a latent infection in sensory neurons, from which it can reactivate periodically. HSV expresses >80 gene products during productive (“lytic”) infection, but only the latency-associated transcript (L...

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Bibliografiske detaljer
Main Authors: Wang, Qing-Yin, Zhou, Changhong, Johnson, Karen E., Colgrove, Robert C., Coen, Donald M., Knipe, David M.
Format: Artigo
Sprog:Inglês
Udgivet: National Academy of Sciences 2005
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC1266038/
https://ncbi.nlm.nih.gov/pubmed/16247011
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0505850102
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