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HCV NS5A abrogates p53 protein function by interfering with p53-DNA binding
AIM: To evaluate the inhibition effect of HCV NS5A on p53 transactivation on p21 promoter and explore its possible mechanism for influencing p53 function. METHODS: p53 function of transactivation on p21 promoter was studied with a luciferase reporter system in which the luciferase gene is driven by...
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| Publicado no: | World J Gastroenterol |
|---|---|
| Main Authors: | , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Baishideng Publishing Group Inc
2004
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4724976/ https://ncbi.nlm.nih.gov/pubmed/15259070 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3748/wjg.v10.i15.2223 |
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