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HCV NS5A abrogates p53 protein function by interfering with p53-DNA binding

AIM: To evaluate the inhibition effect of HCV NS5A on p53 transactivation on p21 promoter and explore its possible mechanism for influencing p53 function. METHODS: p53 function of transactivation on p21 promoter was studied with a luciferase reporter system in which the luciferase gene is driven by...

Täydet tiedot

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Bibliografiset tiedot
Julkaisussa:World J Gastroenterol
Päätekijät: Gong, Guo-Zhong, Jiang, Yong-Fang, He, Yan, Lai, Li-Ying, Zhu, Ying-Hua, Su, Xian-Shi
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: Baishideng Publishing Group Inc 2004
Aiheet:
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC4724976/
https://ncbi.nlm.nih.gov/pubmed/15259070
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3748/wjg.v10.i15.2223
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