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Universal Poisson Statistics of mRNAs with Complex Decay Pathways

Messenger RNA (mRNA) dynamics in single cells are often modeled as a memoryless birth-death process with a constant probability per unit time that an mRNA molecule is synthesized or degraded. This predicts a Poisson steady-state distribution of mRNA number, in close agreement with experiments. This...

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Bibliographische Detailangaben
Veröffentlicht in:Biophys J
1. Verfasser: Thattai, Mukund
Format: Artigo
Sprache:Inglês
Veröffentlicht: The Biophysical Society 2016
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4724633/
https://ncbi.nlm.nih.gov/pubmed/26743048
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bpj.2015.12.001
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