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Puzzling role of genetic risk factors in human longevity: “risk alleles” as pro-longevity variants
Complex diseases are major contributors to human mortality in old age. Paradoxically, many genetic variants that have been associated with increased risks of such diseases are found in genomes of long-lived people, and do not seem to compromise longevity. Here we argue that trade-off-like and condit...
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| 出版年: | Biogerontology |
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| 主要な著者: | , , , , , , , , |
| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
Springer Netherlands
2015
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| 主題: | |
| オンライン･アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4724477/ https://ncbi.nlm.nih.gov/pubmed/26306600 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s10522-015-9600-1 |
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