miR-34a negatively regulates efferocytosis by tissue macrophages in part via SIRT1

Apoptotic cell (AC) clearance (“efferocytosis”) is an evolutionarily conserved process essential for immune health, particularly to maintain self-tolerance. Despite identification of many recognition receptors and intracellular signaling components of efferocytosis, its negative regulation remains i...

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Bibliografiske detaljer
Udgivet i:J Immunol
Main Authors: McCubbrey, Alexandra L, Nelson, Joshua D., Stolberg, Valerie R., Blakely, Pennelope K., McCloskey, Lisa, Janssen, William J., Freeman, Christine M., Curtis, Jeffrey L.
Format: Artigo
Sprog:Inglês
Udgivet: 2015
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4724467/
https://ncbi.nlm.nih.gov/pubmed/26718338
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.1401838
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