TCA cycle and mitochondrial membrane potential are necessary for diverse biological functions

Mitochondrial metabolism is necessary for the maintenance of oxidative TCA cycle function and mitochondrial membrane potential. Previous attempts to decipher whether mitochondria are necessary for biological outcomes have been hampered by genetic and pharmacologic methods that simultaneously disrupt...

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Publicado no:Mol Cell
Main Authors: Martínez-Reyes, Inmaculada, Diebold, Lauren P., Kong, Hyewon, Schieber, Michael, Huang, He, Hensley, Christopher T., Mehta, Manan M., Wang, Tianyuan, Santos, Janine H., Woychik, Richard, Dufour, Eric, Spelbrink, Johannes N., Weinberg, Samuel E., Zhao, Yingming, DeBerardinis, Ralph J., Chandel, Navdeep S.
Formato: Artigo
Idioma:Inglês
Publicado em: 2015
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4724312/
https://ncbi.nlm.nih.gov/pubmed/26725009
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.molcel.2015.12.002
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