Vascular biomarkers derived from dynamic contrast-enhanced MRI predict response of vestibular schwannoma to antiangiogenic therapy in type 2 neurofibromatosis

BACKGROUND: Antiangiogenic therapy of vestibular schwannoma (VS) in type 2 neurofibromatosis can produce tumor shrinkage with response rates of 40%–60%. This study examines the predictive value of parameter-derived MRI in this setting. METHODS: Twelve patients with 20 VSs were recruited. Each had at...

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Detalhes bibliográficos
Publicado no:Neuro Oncol
Principais autores: Li, Ka-Loh, Djoukhadar, Ibrahim, Zhu, Xiaoping, Zhao, Sha, Lloyd, Simon, McCabe, Martin, McBain, Catherine, Evans, D. Gareth, Jackson, Alan
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2016
Assuntos:
Neuroimaging
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4724182/
https://ncbi.nlm.nih.gov/pubmed/26311690
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/neuonc/nov168
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