Neurotensin signaling stimulates glioblastoma cell proliferation by upregulating c-Myc and inhibiting miR-29b-1 and miR-129-3p

BACKGROUND: Neurotensin (NTS) and its primary receptor NTSR1 are implicated in cancer progression. Aberrant expression of NTS/NTSR1 contributes to the proliferation of glioblastoma cells; however, the mechanism is not fully understood. METHODS: Microarray and real-time PCR were performed to identify...

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Vydáno v:Neuro Oncol
Hlavní autoři: Ouyang, Qing, Chen, Gang, Zhou, Ji, Li, Lei, Dong, Zhen, Yang, Rui, Xu, Lunshan, Cui, Hongjuan, Xu, Minhui, Yi, Liang
Médium: Artigo
Jazyk:Inglês
Vydáno: Oxford University Press 2016
Témata:
Basic and Translational Investigations
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4724174/
https://ncbi.nlm.nih.gov/pubmed/26180082
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/neuonc/nov114
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