Anti-RANKL treatment inhibits erosive joint destruction and lowers inflammation but has no effect on bone formation in the delayed-type hypersensitivity arthritis (DTHA) model

BACKGROUND: The aims of the present study were to determine the relationship between bone destruction and bone formation in the delayed-type hypersensitivity arthritis (DTHA) model and to evaluate the effect of receptor activator of nuclear factor κB ligand (RANKL) blockade on severity of arthritis,...

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Detalhes bibliográficos
Publicado no:Arthritis Res Ther
Main Authors: Atkinson, Sara Marie, Bleil, Janine, Maier, René, Kühl, Anja A., Thorn, Mette, Serikawa, Kyle, Fox, Brian, Kruse, Kim, Haase, Claus, Skov, Søren, Nansen, Anneline, Syrbe, Uta
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2016
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4724155/
https://ncbi.nlm.nih.gov/pubmed/26801240
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13075-016-0931-3
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