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Cartilage in facet joints of patients with ankylosing spondylitis (AS) shows signs of cartilage degeneration rather than chondrocyte hypertrophy: implications for joint remodeling in AS

INTRODUCTION: In ankylosing spondylitis (AS), joint remodeling leading to joint ankylosis involves cartilage fusion. Here, we analyzed whether chondrocyte hypertrophy is involved in cartilage fusion and subsequent joint remodeling in AS. METHODS: We assessed the expression of chondrocyte hypertrophy...

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Detalhes bibliográficos
Publicado no:Arthritis Res Ther
Main Authors: Bleil, Janine, Sieper, Joachim, Maier, Rene, Schlichting, Uwe, Hempfing, Axel, Syrbe, Uta, Appel, Heiner
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2015
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4506408/
https://ncbi.nlm.nih.gov/pubmed/26123554
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13075-015-0675-5
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