Structured Illumination Microscopy and a Quantitative Image Analysis for the Detection of Positive Margins in a Pre-Clinical Genetically Engineered Mouse Model of Sarcoma

Intraoperative assessment of surgical margins is critical to ensuring residual tumor does not remain in a patient. Previously, we developed a fluorescence structured illumination microscope (SIM) system with a single-shot field of view (FOV) of 2.1×1.6 mm (3.4 mm(2)) and sub-cellular resolution (4.4...

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Udgivet i:PLoS One
Main Authors: Fu, Henry L., Mueller, Jenna L., Whitley, Melodi J., Cardona, Diana M., Willett, Rebecca M., Kirsch, David G., Brown, J. Quincy, Ramanujam, Nimmi
Format: Artigo
Sprog:Inglês
Udgivet: Public Library of Science 2016
Fag:
Research Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4723137/
https://ncbi.nlm.nih.gov/pubmed/26799613
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0147006
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