Quantitative Segmentation of Fluorescence Microscopy Images of Heterogeneous Tissue: Application to the Detection of Residual Disease in Tumor Margins

PURPOSE: To develop a robust tool for quantitative in situ pathology that allows visualization of heterogeneous tissue morphology and segmentation and quantification of image features. MATERIALS AND METHODS: Tissue excised from a genetically engineered mouse model of sarcoma was imaged using a subce...

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Detalhes bibliográficos
Main Authors: Mueller, Jenna L., Harmany, Zachary T., Mito, Jeffrey K., Kennedy, Stephanie A., Kim, Yongbaek, Dodd, Leslie, Geradts, Joseph, Kirsch, David G., Willett, Rebecca M., Brown, J. Quincy, Ramanujam, Nimmi
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2013
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3688889/
https://ncbi.nlm.nih.gov/pubmed/23824589
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0066198
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