Partially Defective Store Operated Calcium Entry and Hem(ITAM) Signaling in Platelets of Serotonin Transporter Deficient Mice

BACKGROUND: Serotonin (5-hydroxytryptamin, 5-HT) is an indolamine platelet agonist, biochemically derived from tryptophan. 5-HT is secreted from the enterochromaffin cells into the gastrointestinal tract and blood. Blood 5-HT has been proposed to regulate hemostasis by acting as a vasoconstrictor an...

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Detalhes bibliográficos
Publicado no:PLoS One
Main Authors: Wolf, Karen, Braun, Attila, Haining, Elizabeth J., Tseng, Yu-Lun, Kraft, Peter, Schuhmann, Michael K., Gotru, Sanjeev K., Chen, Wenchun, Hermanns, Heike M., Stoll, Guido, Lesch, Klaus-Peter, Nieswandt, Bernhard
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2016
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4723080/
https://ncbi.nlm.nih.gov/pubmed/26800051
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0147664
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