Ibrutinib as Initial Therapy for Patients with Chronic Lymphocytic Leukemia

BACKGROUND: Chronic lymphocytic leukemia (CLL) primarily affects older persons who often have coexisting conditions in addition to disease-related immunosuppression and myelosuppression. We conducted an international, open-label, randomized phase 3 trial to compare two oral agents, ibrutinib and chl...

Full description

Saved in:
Bibliographic Details
Published in:N Engl J Med
Main Authors: Burger, Jan A., Tedeschi, Alessandra, Barr, Paul M., Robak, Tadeusz, Owen, Carolyn, Ghia, Paolo, Bairey, Osnat, Hillmen, Peter, Bartlett, Nancy L., Li, Jianyong, Simpson, David, Grosicki, Sebastian, Devereux, Stephen, McCarthy, Helen, Coutre, Steven, Quach, Hang, Gaidano, Gianluca, Maslyak, Zvenyslava, Stevens, Don A., Janssens, Ann, Offner, Fritz, Mayer, Jiří, O'Dwyer, Michael, Hellmann, Andrzej, Schuh, Anna, Siddiqi, Tanya, Polliack, Aaron, Tam, Constantine S., Suri, Deepali, Cheng, Mei, Clow, Fong, Styles, Lori, James, Danelle F., Kipps, Thomas J.
Format: Artigo
Language:Inglês
Published: 2015
Subjects:
Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4722809/
https://ncbi.nlm.nih.gov/pubmed/26639149
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1056/NEJMoa1509388
Tags: Add Tag
No Tags, Be the first to tag this record!

Similar Items