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Lack of K13 mutations in Plasmodium falciparum persisting after artemisinin combination therapy treatment of Kenyan children

BACKGROUND: Studies in Southeast Asia reported a strong relationship between polymorphisms at the propeller domain of the Kelch 13 (K13) protein encoded by the Plasmodiumfalciparumk13(pfk13) gene and delayed parasite clearance after artemisinin treatment. In Africa, P. falciparum remains susceptible...

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Detalhes bibliográficos
Publicado no:Malar J
Main Authors: Muwanguzi, Julian, Henriques, Gisela, Sawa, Patrick, Bousema, Teun, Sutherland, Colin J., Beshir, Khalid B.
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2016
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4722670/
https://ncbi.nlm.nih.gov/pubmed/26801909
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12936-016-1095-y
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